Tris hydrochloride | CAS 1185-53-1
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Tris hydrochloride · CAS 1185-53-1 · C4H11NO3.ClH. UNII 383V75M34E.
Identification
| CAS Registry Number | 1185-53-1 |
|---|---|
| PubChem CID | 93573 |
| Molecular formula | C4H11NO3.ClH |
| IUPAC name | 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride |
| UNII (FDA) | 383V75M34E |
Computed Descriptors
| Molecular Weight | 157.59 |
|---|---|
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 157.0505709 |
| Monoisotopic Mass | 157.0505709 |
| Topological Polar Surface Area | 86.7 |
| Heavy Atom Count | 9 |
| Formal Charge | 0 |
| Complexity | 54 |
Physical description & handling notes
- Dry Powder; Liquid; Other Solid; Dry Powder
- Hygroscopic solid; [Sigma-Aldrich MSDS]
Regulatory Status
| GHS notification summary | 57.2% (103 / 180) |
|---|
GHS Hazard Classification
| GHS notification summary | 57.2% (103 / 180) |
|---|---|
| Reported hazard statements | H315 (42.2%), H319 (42.2%), H335 (40.6%) |
This chemical does not meet GHS hazard criteria for 57.2% (103 of 180) of all reports.
H315 (42.2%): Causes skin irritation [Warning Skin corrosion/irritation]
Documented Uses
- Used to make surface-active agents and pharmaceuticals, as an emulsifier (for cosmetic creams and lotions, mineral oil, and paraffin wax emulsions), as a biological buffer, and as an alkalizer; [ChemIDplus]
- 2022: 1,000,000 – <2,500,000 lb
- All Other Chemical Product and Preparation Manufacturing
- Pharmaceutical and Medicine Manufacturing
- 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride (1:1): ACTIVE
Synonyms
1185-53-1; Tris hydrochloride; Tris(hydroxymethyl)aminomethane hydrochloride; Tromethamine hydrochloride; 2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride; TRIS HCl; Tris-HCl; Trometamol hydrochloride; Trizma hydrochloride; Tromethamine HCl; 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride; Tris chloride; DTXSID4044373; Tris hydrochloride buffer; UNII-383V75M34E; EINECS 214-684-5
Frequently Asked Questions
What are the CAS number and molecular formula of Tris hydrochloride?
CAS 1185-53-1; molecular formula C4H11NO3.ClH; molecular weight — g/mol.
What other names is Tris hydrochloride known by?
1185-53-1, Tris hydrochloride, Tris(hydroxymethyl)aminomethane hydrochloride, Tromethamine hydrochloride, 2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride, TRIS HCl.
Is Tris hydrochloride classified as hazardous?
57.2% of GHS notifications report no hazard classification (103 of 180).
Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.